A Novel, Minimally Invasive, Paper-based Biomarker Assay for Molecular Diagnosis of Preeclampsia

Preeclampsia is a severe pregnancy condition marked by high blood pressure and proteinuria that can strike at any point throughout pregnancy or immediately after birth. Although the exact cause of this disease is unknown, there are several symptoms associated. The goal of this study is focused on evaluation of biomarker-based assays for molecular the diagnosis of the condition in a sensitive and timely manner. This project involved the use of an immunoassay, fabricated serums samples and a paper-based assay to assess the strength of the presence of placental growth factor (PlGF). This was done to facilitate a proof-of-concept mechanism that can be translated into a molecular diagnostic biosensor