Type of Presentation
Poster
Type of Project
Independent Research
Presenter 1 Program
Biotechnology
Presenter 1 Location
Harrisburg
Project Description
Preeclampsia is a severe pregnancy condition marked by high blood pressure and proteinuria that can strike at any point throughout pregnancy or immediately after birth. Although the exact cause of this disease is unknown, there are several symptoms associated. The goal of this study is focused on the evaluation of biomarker-based assays for molecular diagnosis of the condition in a sensitive and timely manner. This project involved the use of an immunoassay, fabricated serum samples, and a paper-based assay to assess the strength of the presence of the placental growth factor (PlGF). This was done to facilitate a proof-of-concept mechanism that can be translated into a molecular diagnostic biosensor
Faculty Member
Leena Pattarkine
Included in
Congenital, Hereditary, and Neonatal Diseases and Abnormalities Commons, Diagnosis Commons
A Novel, Minimally Invasive, Paper-based Biomarker Assay for Molecular Diagnosis of Preeclampsia
Preeclampsia is a severe pregnancy condition marked by high blood pressure and proteinuria that can strike at any point throughout pregnancy or immediately after birth. Although the exact cause of this disease is unknown, there are several symptoms associated. The goal of this study is focused on the evaluation of biomarker-based assays for molecular diagnosis of the condition in a sensitive and timely manner. This project involved the use of an immunoassay, fabricated serum samples, and a paper-based assay to assess the strength of the presence of the placental growth factor (PlGF). This was done to facilitate a proof-of-concept mechanism that can be translated into a molecular diagnostic biosensor